← All Tools

OMIM

VERIFIED

## Connections

genetics disease mendelian

What It Does

  • Comprehensive gene-disease relationship catalog
  • Detailed phenotype descriptions with inheritance patterns
  • Allelic variants with clinical significance
  • Gene function summaries from literature
  • MIM numbers as universal identifiers

How to Use

### Web

1. Go to https://omim.org

2. Search: "STRC" or "DFNB16" (the deafness locus)

3. Read: gene entry, phenotype entry, allelic variants

### Key STRC Entries

  • STRC gene: MIM #606440
  • DFNB16 (deafness): MIM #603720
  • Inheritance: Autosomal recessive

### API (requires key)


        # Apply for API key at https://omim.org/api
        curl "https://api.omim.org/api/entry?mimNumber=606440&apiKey=YOUR_KEY&format=json"

Verified Status

VERIFIED — STRC (MIM #606440) linked to DFNB16 hearing loss. Autosomal recessive. Multiple pathogenic variants documented.

STRC Research Usage

  • STRC Gene — canonical gene-disease reference
  • STRC Hearing Loss — phenotype description
  • DFNB16: bilateral sensorineural hearing loss, typically moderate-to-severe, stable

Results (April 2026)

  • OMIM API requires authentication — allelic variant list not programmatically accessible without key
  • Known from literature: OMIM lists ~5-10 high-confidence allelic variants for STRC
  • STRC only associated with DFNB16 hearing loss — no other phenotypes
  • API key applied for — OMIM requires institutional review (not instant). Web interface works for manual lookup. Allelic variant data accessible through web.

Results (April 2026)

  • OMIM API requires authentication — allelic variant list not programmatically accessible without key
  • Known from literature: OMIM lists ~5-10 high-confidence allelic variants for STRC
  • STRC only associated with DFNB16 hearing loss — no other phenotypes
  • API key applied for — OMIM requires institutional review (not instant). Web interface works for manual lookup. Allelic variant data accessible through web.