SWISS-MODEL

What It Does

• Builds 3D protein models by homology to known experimental structures
• Template search across PDB
• Model quality estimation (GMQE, QMEANDisCo)
• Oligomeric state prediction

How to Use

### Web Interface

1. Go to https://swissmodel.expasy.org

2. Paste protein sequence or UniProt ID

3. Choose template or let auto-select

4. Download resulting model (PDB format)

### API

        # Submit modeling job
        curl -X POST https://swissmodel.expasy.org/automodel \
          -H "Content-Type: application/json" \
          -d '{"target_sequences": "MVLSPA...", "project_title": "STRC"}'
        

Verified Status

VERIFIED — STRC has ZERO pre-computed homology models in SWISS-MODEL Repository (no experimental homolog in PDB). AlphaFold predictions are the only available 3D structures. SWISS-MODEL is NOT useful for STRC (no close experimental homolog in PDB). AlphaFold predictions generally superior for STRC.

STRC Research Usage

• Secondary validation of AlphaFold predictions
• Useful when experimental structures of homologs exist

STRC Research Usage

• Secondary validation of AlphaFold predictions
• Useful when experimental structures of homologs exist