Part 4

Computational Tools

Comprehensive toolkit for independent genetic variant research and hearing loss genetics analysis.

47 computational tools used in STRC variant analysis. All freely accessible for independent research. View English version for complete details.

Key Tools Used

Hermes (AI Agent)

Open source AI agent for autonomous research

AlphaMissense

Variant pathogenicity prediction (E1659A: 0.9016)

AlphaFold 3 Server

16 experiments testing mini-STRC hypothesis

gnomAD

Population frequency analysis (E1659A: 0 alleles)

Ensembl REST API

Genomic coordinates and PAM site analysis

UniProt

Conservation analysis across 9 mammalian species

Research Impact

47
Computational tools
16
AlphaFold 3 experiments
$50-100
Total AI cost

View full English version for complete tool descriptions and usage details.